Our Publications (selected)

* Co-first author; Founders

• Li, C., Zamore, P. D. (2012). Chapter 18. RNA Interference and Small RNA Analysis. Molecular Cloning (4th).18, 1415-1480

• Vagin, V. V., Sigova, A., Li, C., Seitz, H., Gvozdev, V., Zamore, P. D. (2006) A distinct small RNA pathway silences selfish genetic elements in the germline.  Science. 313, 320-324.

• Ghildiyal, M., Seitz, H., Horwich, M. D., Li, C., Du, T., Lee, S., Xu, J., Kittler, E. L., Zapp, M. L., Weng, Z., Zamore, P. D. (2008) Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells.  Science. 320, 1077-1081.

• Li, C., Vagin, V. V., Lee, S., Xu, J., Ma, S., Xi, H., Seitz, H., Horwich, M. D., Syrzycka, M., Honda, B. M., Kittler, E. L., Zapp, M. L., Klattenhoff, C., Schulz, N., Theurkauf, W. E., Weng, Z., Zamore, P. D.(2009). Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies.  Cell. 137, 509-521.

• Klattenhoff, C., Xi, H., Li, C., Lee, S., Xu, J., Khurana, J. S., Zhang, F., Schultz, N., Koppetsch, B. S., Nowosielska, A., Seitz, H., Zamore, P. D., Weng, Z., Theurkauf, W. E. (2009) The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters.  Cell. 138, 1137-1149.

• Carone, B. R., Fauquier, L., Habib, N., Shea, J. M., Hart, C. E., Li, R., Bock, C., Li, C., Gu, H., Zamore, P. D., Meissner, A., Weng, Z., Hofmann, H. A., Friedman, N., Rando, O. J. Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. (2010)  Cell. 143, 1084-1096.

• Khurana, J. S., Wang, J., Xu, J., Koppetsch, B. S., Thomson, T. C., Nowosielska, A., Li, C., Zamore, P. D., Weng, Z., Theurkauf, W. E. (2011) Adaptation to P element transposon invasion in Drosophila melanogaster.  Cell. 147, 1551-1563.

• Han B.W.*, Wang W.*, Li C., Weng Z., and Zamore P.D. (2015). Secondary piRNA-guided cleavage initiates Zucchini-dependent, phased, primary piRNA production.  Science. 348, 817-821.

• Xie J, Tai PWL, Brown A, Gong S, Zhu S, Wang Y, Li C., Colpan C, Su Q, He R, Ma H, Li J, Ye H, Ko J, Zamore PD, Gao G. (2020). Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold.  Mol Ther. 28, 422-430.